Human Health TDC
AMAP Thematic Data Centres compile data from relevant monitoring and research activities and make them available under strict conditions that protect the rights of data originators. AMAP TDCs are located at established centres with appropriate expertise and facilities for conducting the types of international data handling required. For more information, please visit the main AMAP website.
It is also possible to browse and query the full list of projects.
To edit or add records to any of the catalogs, log in or create an account.
This study investigates possible detrimental effects on the immune system of Inuit infants which may be induced by prenatal and postnatal (breast feeding) exposure to persistent environmental contaminants such as organochlorine compounds. These substances accumulate in the body of Inuit women in part due to their consumption of sea mammal fat and can be transferred to the foetus during pregnacy and to the infant during breast feeding. Immune system function will be evaluated using several parameters: 1) the level of antibody produced by the infant following Haemophilus influenza immunization; 2) the level of proteins which protect the infant against bacterial infections (complement system) before its immune system is fully developed; and 3) the level of chemical messengers (cytokines) which enable the various cells of the immune system to communicate with each other, thereby maintaining its proper function and assuring the protection of the infant against bacteria, parasitic and viral infections.
Objectives: 1. Locate and assemble scientific data from the U.S. Arctic on the concentrations and effects of POPs in all compartments (e.g., marine and terrestrial biota, abiotic substrates) of the Arctic. 2. Evaluate, analyze and summarize these scientific data from the U.S. Arctic into text suitable for inclusion in a new (second) AMAP publication on POPs. 3. Disseminate the summarized information via a U.S. AMAP Internet page that is directly linked to the current International AMAP Internet page. Summary (Abstract): The Arctic Monitoring and Assessment Programme (AMAP) was established in 1991 and given the responsibility of monitoring the concentrations and assessing the effects of selected anthropogenic pollutants in all compartments of the Arctic. The first AMAP assessment report, published in 1998, points out gaps in our current understanding of contaminant inputs, their transport processes and food web interactions. In addition, the AMAP report noted a serious lack of information about persistent organic pollutants (POPs) in the U.S. and Russian Arctic. Thus, the recommendations of the first AMAP report were to: monitor spatial distribution, contaminant levels and biological effects of POPs; improve the understanding of the adverse effects of POPs on human populations; and fill existing data gaps, specifically in the U.S. and Russia. In this work, we plan to identify sources of scientific information (e.g., published reports, datasets) on POPs in the U.S. Arctic and obtain these data for AMAP. Once data sources are identified, a small group of scientific experts will be assembled for a workshop to determine if any pertinent sources have been overlooked and to give advice on how best to evaluate, analyze, summarize and disseminate the information obtained. A working database will be designed so that the data and scientifically important findings or conclusions from each study can be organized and evaluated. Data will be analyzed statistically, as appropriate, to determine spatial and temporal trends. The data and scientific findings that have been collected and analyzed will then be summarized into text, for inclusion in the next AMAP publication on POPs. This major effort of synthesizing the existing data from the U.S. Arctic will ensure that the AMAP report adequately presents the accomplishments of U.S. scientists and research programs. The written publication and the summarized U.S. POPs data will also be presented as a U.S. AMAP Internet page linked to the International AMAP Internet page.