The aim of the present project is to continue the monitoring of contaminants Greenland biota in order to detect temporal and geographical changes including screening and retrospective analyses of "new" contaminants of increasing concern. Furthermore, temporal trend monitoring of selected biomarkers (e.g. bone mineral density and histopathological changes) in polar bear are included in the monitoring as these have shown to be sensitive to stressors such as contaminants. The project will provide the fundamental basic knowledge of temporal trends and feed into international geographical trend studies of mainly long range transport of contaminants in the atmosphere and biota to Greenland. The project will provide an important input to international convention works such as the Stockholm Convention and the Long-range Trans-boundary Air Pollution.