Controlled dose-control experiment on POP in sledge dogs

Updated 2005-09-30

Organochlorines (OCs) concentrate through the arctic marine food webs and are stored in the adipose tissue due to their high lipophilic and persistent characteristics. The polar bears receive high doses of POPS through their diet and a controlled experimt was need to resolve effect on the immune system and effects on internal organs. Such a controlled experiment on sledge dogs as a replacement test organism for the polar bear was conducted from 2004-2006 to investigate dose-response effects.

This is a National Implementation Plan (NIP) project

Time frame

Project time span
2003 - 2006
Data collection
2004 - 2006
Data processing
2004 - 2006
Data reporting
2004 - 2006

Contact information

Contact person
Rune Dietz
Frederiksborgvej 399 P.O.Box 358 DK-4000 Roskilde, Denmark
+45 46301938
+45 46301914
Other project contacts
Christian Sonne

Parameters and Media

Parameter groups measured/observed/modelled
Biological effects
Persistent organic pollutants (POPs)
Media sampled/studied/modelled
Marine mammals


Regions studied
Persistent organic pollutants (POPs)

Data availability

Are data archived or planned to be archived at an AMAP Thematic Data Centre?
If no (or only part of data are reported to a TDC), where and how are (other) data stored?
No comparable data exist from other countries. Furthermore the data format are not suitable for such an dose-response experiment
Samples/specimens archived in specimen banks?
Specimen banking information

Tissues of slegde dogs

Methods & Procedures

Not specified

Additional Information

Is this a bi- AND multi-lateral project (i.e. a project involving cooperation between different countries)?
Other institutes involved in the project

Hvidovre Hospital, Denmark Kgl. Veterinær og Landbohøjskole, Denmark Carleton University, Canadian Wildlife Service, Canada National Water Research Institute, Burlington, Canada Norgen Tekniske og Naturvidenskabelige Universitet, Trondheim, Norway

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