The full list of projects contains the entire database hosted on this portal, across the available directories. The projects and activities (across all directories/catalogs) are also available by country of origin, by geographical region, or by directory.
Short Term i) to provide additional information for use in updating health advisories. Long Term i)to investigate the fate and effects of contaminant deposition and transport to the Yukon, allowing Northerners to better manage the issue of contaminants. ii)to determine levels of contaminants for use in long term trend monitoring.
1. Continue to investigate spatial and temporal patterns in mercury concentrations in fish in lakes in the Mackenzie River Basin with a focus on predatory fish in smaller lakes near Fort Simpson but also including Great Bear Lake 2. Assess temporal trends in mercury concentrations and influencing factors, e.g., climate change 3. Conduct sediment core studies as opportunities allow to characterize long-term trends in mercury deposition and productivity 4. Integrate the findings of this study with our mercury trend monitoring in Great Slave Lake and the western provinces.
The main purpose of this research is to examine the consequences of in utero exposure to PCBs on Inuit infants, from birth to 11 months of age. Of particular interest is the impact of PCBs and mercury exposure on newborn’s thyroid hormones, physical growth, physical and central nervous system maturity, on infant’s overall health, mental, psychomotor and neurobehavioral development, and on functional and neural impairment in the domains of visual and spatial information processing. The proposed project is designed to replicate and extend previous findings by studying a more highly exposed cohort of infant, and using new infant assessment paradigms that have been linked to specific brain regions and neural pathways and, therefore, have a potential to provide information regarding possible mechanisms of action. The second objective of this research is to document the exposure to heavy metals, organochlorines and polyunsaturated fatty acids of newborns from selected communities in Nunavik. This ongoing effect study provides the opportunity to perform long time trend analysis of human exposure (data available for same communities since 1993).
Case control study of the possible effect of smokinf status on the acumulation of plasma POP in 48 Greenlandic hunters.
The purpose of this research is to examine the long term consequences of prenatal exposure to PCBs and MeHg. This project is designed to study domains of effects overlooked in most of the previous studies. Of particular interest is the impact of exposure on neurophysiological and neurological endpoints that could be related to learning difficulties and disabilities. This study will support the health risk assessment process by providing dose-effect analysis for the neurophysiological and neurological domains of effects of preschool age children from Nunavik (Canada). The total sample will comprise 100 Nunavik Inuit children aged 5-6years. The following exclusion criteria will be applied: Apgar below 5 at 5 minutes of life, evidence of birth trauma, less than 37 weeks of gestation and less than 2500 grams at birth, congenital or chromosomal anomalies, epilepsy, significant disease history, major neurological impairment, fetal alcohol syndrome, presence of facial dysmorphologies associated with fetal alcohol effects.
Analysis of POP and heavy metals, in men and women (pregnant and non-pregnant), time and spatial trends, lifestyle factors, diet and smoking, biomarkers
Humans in Greenland are exposed to higher intakes of some contaminants from the diet than in most of Europe and North America. The objective of the study is to screen the most important local diet items in West Greenland for cadmium, mercury, selenium and organochlorine contaminants. Mammals, birds, fish and invertebrates, mainly marine species are being analysed.
In Greenland lead exposure to humans from the local diet in general is very low. But the use of lead shot introduces a significant amount of lead in locally hunted birds. Human exposure to lead from the use of lead shot will be assessed by analysing breast meat from thick-billed murre and common eider. In common eider, the Greenland species which is suspected to be most exposed to lead toxicity, the frequency of embedded shots and of shots in the gizzard will be studied, and wing bones will be analysed for lead as an indicator of long-term exposure to lead.
The objective of the study is to establish baseline levels of specific heavy metal and organochlorine contaminants in the blood of women and their newborns, from communities in the Inuvik Region. The study examines traditional food consumption as a possible contaminant exposure pathway, while measuring organochlorines and metals in maternal and cord blood, as well as mercury levels in maternal hair. Collection of data from this region will complete the Northwest Territories/Nunavut database on maternal and cord blood. There were 104 women participating in this study from Inuvialuit, Gwich'in and non-native backgrounds. The results are similar to existing data from other regions in the Canadian north and confirm the importance of traditional foods among women of reproductive age. Exposure levels to contaminants were generally within guideline levels with only a few exceptions. Communication of results to the communities will continue until June 2000. Objectives: 1.To obtain regional values for the concentrations of organochlorine and metal contaminants in maternal and umbilical cord blood samples, and the concentration of mercury in hair samples from pregnant women in the Inuvik region. 2.To assess exposure to these contaminants through the frequency of traditional/country food intake and certain other lifestyle factors. 3.To describe any relationship between contaminant levels in blood and hair samples and frequency of consumption of traditional/country foods and selected lifestyle factors.
Specifically, this project aims to: 1. Review and organize the reported social and cultural benefits and risks associated with a traditional diet and related activities (hunting, preparation, consumption); 2. Develop and apply a survey tool to increase our understanding of the determinants of diet behavior; 3. Develop a conceptual framework for the ordered presentation of this information; 4. Link this framework with those organizing information on health and economic benefits and risks associated with traditional foods.
The objectives of the centre are: - to provide access to data from recent human health monitoring and research activities conducted as part of the AMAP national implementation plans. - to provide a means to ensure treatment of data in a consistent manner, uniform statistical analysis etc., including application of objective quality assurance procedures. - to begin the process of establishing a long-term archive of relevant Arctic monitoring data for use in future assessments of temporal trends etc. - to meet the ministerial request from the Alta Conference to include human health data in the AMAP thematic data centres.